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The functional order maintained within living systems seems to defy the Second Law; nonequilibrium thermodynamics describes how such systems come to terms with entropy.
Ilya Prigogine
Equilibrium thermodynamics was an achievement of the nineteenth century, nonequilibrium thermodynamics was developed in the twentieth century, and Onsager's relations mark a crucial point in the shift of interest away from equilibrium to non-equilibrium.
Ilya Prigogine