Genotype Quotes

The idea that a few people have about the gene being the target of selection is completely impractical; a gene is never visible to natural selection, and in the genotype, it is always in the context with other genes, and the interaction with those other genes make a particular gene either more favorable or less favorable. In fact, Dobzhanksy, for instance, worked quite a bit on so-called lethal chromosomes which are highly successful in one combination, and lethal in another. Therefore people like Dawkins in England who still think the gene is the target of selection are evidently wrong. In the 30s and 40s, it was widely accepted that genes were the target of selection, because that was the only way they could be made accessible to mathematics, but now we know that it is really the whole genotype of the individual, not the gene. Except for that slight revision, the basic Darwinian theory hasn't changed in the last 50 years. (Ernst Mayr)
[T]he psychic and physical characteristics of human beings, and the differences between individuals, are the consequence of an interaction between the genes that are present in the fertilized egg and the sequence of environmental circumstances that the developing organism experiences during its entire life history. With a few exceptions, like cystic fibrosis where possession of the defective genotype leads ineluctably to the disease, or language acquisition where the language spoken depends only on experience and not at all on genotype, human characteristics are all subject to this interaction of forces. There are, moreover, random events in cell growth and differentiation that are neither genetic nor environmental in the usual sense, and which play an extremely important part in development, especially in behavioral traits. View quote
Richard Lewontin
From negative capability, embodied in institutions, practices, and modes of consciousness, a wealth of practical competitive advantages result. However, negative capability is not merely a source of such advantages; it is a direct manifestation of our godlike power to outreach the established settings of action and thought and to split the difference between being inside a framework and being outside it. History, we may suppose, selects for this advantage more powerfully and above all more quickly than any form of natural competition for reproductive success, at the level of the species, the organism, or the genotype, can exert selective influence. Negative capability is power to the mind in its least modular and computable aspectsː mind-making continued through politics. View quote
Roberto Mangabeira Unger