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Food should come from the place of its origin, and stay there. It shouldn't spend its time crisscrossing the globe for the sake of profit. We went down that path once, and it brought us to ruin.
Paolo Bacigalupi
Even a single missed crucial consideration could vitiate our most valiant efforts or render them as actively harmful as those of a soldier who is fighting on the wrong side. The search for crucial considerations (which must explore normative as well as descriptive issues) will often require crisscrossing the boundaries between different academic disciplines and other fields of knowledge. As there is no established methodology for how to go about this kind of research, difficult original thinking is necessary.
Nick Bostrom