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Let's instead define life very broadly, simply as a process that can retain its complexity and replicate. What's replicated isn't matter (made of atoms) but information (made of bits) specifying how the atoms are arranged. When a bacterium makes a copy of its DNA, no new atoms are created, but a new set of atoms are arranged in the same pattern as the original, thereby copying the information. In other words, we can think of life as a self-replicating information-processing system whose information (software) determines both its behavior and the blueprints for its hardware.
Max Tegmark
[The smallest bacterium] is so much more like people than Stanley Miller's mixtures of chemicals, because it already has these system properties. So to go from a bacterium to people is less of a step than to go from a mixture of amino acids to that bacterium.
Lynn Margulis
In the long run, the most vicious predators, like most dread disease-causing microbes, bring about their own ruin by killing their victims. Restrained predation-the attack that doesn't kill or does kill only slowly-is a recurring theme in evolution. The predatory precursors of mitochondria invaded and exploited their hosts, but the prey resisted. Forced to be content with an expendable part of the prey (its waste)... some mitochondria precursors grew but never killed their providers. ...The original prey was probably a larger bacterium like Thermoplasma.
Lynn Margulis
I wish, I wish I were a poisonous bacterium.
Dorothy Parker
Simonson, in rubber jacket and similar galoshes, bound with whip-cord over woolen socks (he was a vegetarian and did not use the skin of animals), was also awaiting the departure of the party. He stood near the entrance of the house, writing down in a note-book a thought that occurred to him. "If,” he wrote, "a bacterium were to observe and analyze the nail of a man, it would declare him an inorganic being. Similarly, from an observation of the earth's surface, we declare it to be inorganic. That is wrong.”.
Leo Tolstoy
You can find bacteria everywhere. They're invisible to us. I've never seen a bacterium, except under a microscope. They're so small, we don't see them, but they are everywhere.
Bonnie Bassler
As I thought about this, I noted that the bacterium is just a physical system; it's just a bunch of molecules that hang together and do things to one another. So, I wondered, what characteristics are necessary for a physical system to be an autonomous agent? After thinking about this for a number of months I came up with a tentative definition. My definition is that an autonomous agent is something that can both reproduce itself and do at least one thermodynamic work cycle. It turns out that this is true of all free-living cells, excepting weird special cases. They all do work cycles, just like the bacterium spinning its flagellum as it swims up the glucose gradient. The cells in your body are busy doing work cycles all the time.
Stuart Kauffman