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Once you're labeled as mentally ill, and that's in your medical notes, then anything you say can be discounted as an artefact of your mental illness.
Hilary Mantel
Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by the same inhibitors. Thus the system is most unlikely to be a complete artefact and is very probably closely related to genuine protein synthesis.
Francis Crick
Privacy is a luxury; to buy it you need to be able to buy space and fit locks, to switch off the phone and live without fear of dependency on others. Privacy is a peculiarly twentieth-century concept, an artefact of the Western urban middle classes: Before then, only the super rich could afford it, and since the invention of e-mail and the mobile phone, it has largely slipped away.
Charles Stross
I've been thinking like this since 1968, talking about it like this since 1980, but I never knew what... how it would come or what it would be. In the last few years, with the rise of a technological, a cultural artefact like the internet, I now see how it will make its way into the world. We are building the nervous system of the human oversoul. We are individual units operating under social rules that are pushing us ever closer toward dissolving our societies... societies-human groups run by rules-into telepathic collectivities of some sort. ... We have come to the end of our sojourn in matter. We have come to the end of our separateness.
Terence McKenna
Today everyone knows that inequality is wrong. A century ago everyone knew that gay sex was wrong. The intuitions people have on moral questions are intensely felt. They are also shallow and transient to the last degree.... Justice is an artefact of custom. Where customs are unsettled its dictates soon become dated. Ideas of justice are as timeless as fashion in hats.
John N. Gray
Only the misapprehension that [Paglia] can be wise like lightning could explain her brief appearance, in Inside Deep Throat, to tell us that the cultural artefact in question was 'an epochal moment in the history of modern sexuality.' On the contrary, it was a moronic moment in the history of exploitation movies made by people so untalented that they can't even be convincing when they masturbate.
Clive James
Discourse occurs at the silent level of the artefact and is continuously presenced in the world as such. It is a discourse which is not, and cannot be, articulated in speech.
Christopher Tilley