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The best estimates are that it takes a minimum of fifty thousand years for an adaptation to show up in the human genome. This is called evolutionary lag... Our hunter-gatherer ancestors had a very different lifestyle...
Daniel Levitin
I respect and value the ideals of rugged individualism and self-reliance. But rugged individualism didn't defeat the British, it didn't get us to the moon, build our nation's highways, or map the human genome. We did that together. This is the high call of patriotism.
Cory Booker
By being able to write a genome and plug it into an organism, the software, if you will, changes the hardware.
Barry Schuler
Living in your genome is the history of our species.
Barry Schuler
Your genome knows much more about your medical history than you do.
Danny Hillis
The overall view of the human genome project has been one of great excitement and positive press, but there are people who have concerns that are quite reasonable, and they are frightened of things they don't understand.
Thomas R. Cech
I am tired of hearing that the DNA in my cells nucleus is the complete blueprint of what is, or could be, me. There is more to me than that. The sequence of my nuclear DNA is not "My Genome."
Gottfried Schatz
Why do people believe that there are dangerous implications of the idea that the mind is a product of the brain, that the brain is organized in part by the genome, and that the genome was shaped by natural selection?
Steven Pinker
I do hereby and forever abandon abandoning all hope. Honestly, I give up on giving up. I'm just not cut out to be some hopeless, disillusioned wretch with no aspirations for the rest of the eternity, sprawled catatonic in my own feces on a cold stone floor. In all probability the Human Genome Project will, someday, find that I carry some recessive gene for optimism, because despite all my best efforts I still can't scrape together even a couple of days of hopelessness. Future scientists would call it Pollyanna Syndrome, and if forced to guess, I'd say that mine has been a way-long case of history chasing rainbows.
Chuck Palahniuk
If you use conventional data compression on the [human brain's] genome, you get about 23 million bytes (a small fraction of the size of Microsoft Word), which is a level of complexity we can handle.
Ray Kurzweil
I firmly believe that the next great breakthrough in bioscience could come from a 15-year-old who downloads the human genome in Egypt.
Thomas Friedman
At the hearing I not only described the EST method and the rapid rate of human gene discovery but also voiced by concerns about NIH's patent efforts, a subject I was glad to get out in the open. The room went quiet as many were startled by this discovery and then Watson suddenly shouted that it was "sheer lunacy" to file such patents, adding that "virtually any monkey" could use the EST method and that he was "horrified." As Cook-Deegan, a Duke University genome discussant, described the event, "Watson was lying in wait and took aim with heavy artillery." Cook-Deegan, who was Watson's assistant at the time, told me later that Watson had practiced the lines for a week prior to the hearing.
Craig Venter
I think there are people who's lives have been saved because of the study of the genome.
Francis Collins
I would not expect religion to be the right tool for sequencing the human genome and by the same token would not expect science to be the means to approaching the supernatural. But on the really interesting larger questions, such as ‘Why are we here?' or ‘Why do human beings long for spirituality?,' I find science unsatisfactory. Many superstitions have come into existence and then faded away. Faith has not, which suggests it has reality.
Francis Collins
As someone who's had the privilege of leading the human genome project, I've had the opportunity to study our own DNA instruction book at a level of detail that was never really possible before. It's also now been possible to compare our DNA with that of many other species. The evidence supporting the idea that all living things are descended from a common ancestor is truly overwhelming. I would not necessarily wish that to be so, as a Bible-believing Christian. But it is so. It does not serve faith well to try to deny that.
Francis Collins
But this (a listing of illustrations of how the genome can change other than by mutations) doesn't constitute a crisis-it's a very interesting finding that shows that variation in a genome can arise by processes other than mutation of an organism's own DNA. The disposition of that variation still must occur via either natural selection (it can be good or bad) or genetic drift (no effect on fitness). This hasn't really changed the theory of evolution one iota, though it's changed our view of where organisms can acquire new genes.
Jerry Coyne
The main purpose of most genes in the human genome is regulating the expression of other genes in the genome.
Matt Ridley
The genome is littered, one might almost say clogged, with the equivalent of computer viruses, selfish, parasitic stretches of letters which exist for the pure and simple reason that they are good at getting themselves duplicated. We are full of digital chain letters and warnings about marmalade.
Matt Ridley
The classification of humans into five continental based races is perfectly reasonable and is supported by genome clustering studies. In addition, classification into the three major races of African, East Asian and European is supported by the physical anthropology of human skull types and dentition.
Nicholas Wade
There are two important factors to consider in the emergence of social change. One is that a society develops through changes in its institutions, which are blends of culture and genetically shaped social behavior. The other is that the genes and culture interact. This may seem paradoxical to anyone who considers genes and culture to be entirely separate realms. But it is scarcely surprising from an evolutionary perspective, given that the genome is designed to respond to the environment, and a major component of the human environment is society and its cultural practices.
Nicholas Wade
The various races and ethnicities into which humans have evolved represent a grand experiment in which nature has tested out some of the variations inherent in the human genome. The experiment is not being conducted in our interests - it has no purpose or goal - yet it offers considerable benefits. Instead of there being a single type of human society, there are many, creating a rich diversity of cultures whose more promising features can be adopted and improved on by others.
Nicholas Wade
I have had my genome fully sequenced and have learned a great deal about which medications I would respond to and which might or would induce major side effects, along with knowing many medical conditions for which I'm particularly susceptible.
Eric Topol
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