One of the most fundamental principles of Lavoisier's chemistry was the use of numbers, notably in relation to what we often call today the principle of conservation of mass... The principle implies that the experimenter must not only keep account of all the reacting solids and liquids, but also the gases-that is, all of the products. ...This rule led to quantitative experiments. Lavoisier was not the first person to use numbers in chemistry but he was a pioneer in using such numerical measurements as the basis of his system of chemistry. ...When Lavoisier first announced this law, chemists generally believed in... "phlogiston" which supposedly entered into chemical reactions (such as combustion) but had no weight. It was a radical step, therefore, for Lavoisier to base a system of chemistry on a balance of weights and to maintain that chemistry is not concerned with weightless "substances." ...this was indeed a chemical revolution.
Antoine Lavoisier
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