Science fiction may be defined as that branch of literature which deals with the response of human beings to advances in science and technology. Actual change in science and technology, occurring quickly enough and striking deeply enough to affect a human being in the course of his normal lifetime, is a phenomenon peculiar to the world only since the Industrial Revolution ... The first well-known writer who responded to this new factor in human affairs by dealing regularly with science fiction, by studying the effect of additional scientific advance upon mankind ... was Jules Verne. In the English language, the early master was H. G. Wells. Between them, they laid the foundation for every theme upon which science fiction writers have been ringing variations ever since.
Isaac Asimov
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Pity those-adventurers, adolescents, authors of young adult fiction-who make their way in the borderland between worlds. It is at worst an invisible and at best an inhospitable place. Build your literary house on the borderlands, as the English writer Philip Pullman has done, and you may find that your work is recommended by booksellers, as a stopgap between installments of Harry Potter, to children who cannot (one hopes) fully appreciate it, and to adults, disdainful or baffled, who 'don't read fantasy.' Yet all mystery resides there, in the margins, between life and death, childhood and adulthood, Newtonian and quantum, 'serious' and 'genre' literature. And it is from the confrontation with mystery that the truest stories have always drawn their power.
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Jacob Bronowski