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Reason, observation, and experience; the holy trinity of science.
Robert G. Ingersoll
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My experience is that people are most likely to listen to reason when in bed.
Groucho Marx
A second reason why science cannot replace judgement is the behavior of financial markets.
Martin Feldstein
RATIONAL, adj. Devoid of all delusions save those of observation, experience and reflection.
Ambrose Bierce
As soon as questions of will or decision or reason or choice of action arise, human science is at a loss.
Noam Chomsky
Experience has always shown, and reason also, that affairs which depend on many seldom succeed.
Francesco Guicciardini